Senior Investigator, ImmunoTechnology Section
Vaccine Research Center, NIAID, NIH
Bethesda, MD 20892 USA
Mario Roederer, Ph.D., is a tenured Senior Investigator at the Vaccine Research Center (VRC) at the National Institutes of Health. He leads the ImmunoTechnology Section, and directs the Flow Cytometry Core and the Nonhuman Primate Immunogenicity Core. In addition, Dr. Roederer oversees the Translational Research Program that supervises all animal models at the VRC, and serves as Chair of the VRC Animal Care and Use Program.
Dr. Roederer has a B.S. in Chemistry from Harvey Mudd College, a Ph.D. in Cell Biology from Carnegie Mellon, and postdoctoral training with Dr. Leonard Herzenberg at Stanford University. At the VRC, he has mentored more than three dozen students and postdoctoral fellows.
Dr. Roederer’s has co-authored more than 350 publications, garnering over 52,000 citations with an “h-index” of 116. He has given over 340 invited presentations on his research. He co-authored eight patents ranging from chemistry to immunology to software solutions, yielding over $10M in royalties for Stanford and NIH, and was inducted into the Stanford Inventors Hall of Fame. He authored five software titles in world-wide use, including FlowJo, the standard for flow cytometry data analysis.
His research combines advanced technology development in the setting of single cell analysis (integrating both flow cytometry and transcriptomics), with basic T and B cell immunology. Over the past 25 years, he led the effort to the develop the state-of-the-art 30+ color flow cytometry. This effort spawned a wide range of technology and assay development efforts, resulting in novel analysis tools, probes, assays, reagents, and applications.
Basic research projects include understanding the complete repertoire of T cell functions and antibodies needed to protect against pathogens or cancers, how these functions can be elicited by vaccines, and modulated by host genetics and microbiomes. In addition, his laboratory has extensive experience in developing and applying the nonhuman primate model for research and translation. In the past 5 years, the laboratory has generated hundreds of unique monoclonal antibodies against SIV, encephalitis viruses, and NHP lymphocytes to support the NHP model for vaccine and therapeutic testing.
Muzlifah Haniffa is a Wellcome Trust Senior Research Fellow, Lister Institute Research Fellow and Consultant Dermatologist based in Newcastle University. She graduated from medical school in Cardiff and trained as a junior doctor in Cambridge. She received her dermatology specialist training in Newcastle. She was awarded an Action Medical Research Training Fellowship and a Wellcome Trust Clinical Intermediate Fellowship. Muzz was the recipient of the Academy of Medical Sciences Foulkes Foundation Medal (2019) and the European Federation of Immunological Societies ACTERIA Prize in Immunology and Allergology (2018).
Muzz is a leading member of the Human Cell Atlas initiative and pioneered the application of single cell genomics to decode the developing human immune system, and the human skin in health and disease.
Dr. Kristy Wolniak is an assistant professor in Hematopathology at Northwestern Medicine and served as the medical director of the clinical flow cytometry laboratory for 5 years. Currently she is the Phase I Curriculum Director for the Northwestern University Feinberg School of Medicine. In the field of flow cytometry and hematopathology Dr. Wolniak has active involvement in the national and international communities and is involved in establishing consensus guidelines for malignancy evaluation by flow cytometry. She is currently the Senior Councilor of Education for the International Clinical Cytometry Society and served as the chair of the Examination Committee in the development of the ASCP-BOC Specialist in Cytometry certification. In the field of education, Dr. Wolniak is working to bring active learning to all levels of pathology and medical education.
Florian obtained his MSc from the University of Vienna (Austria) in 2008 and his PhD from the University of Zurich (Switzerland) in 2014. Currently, he is working as an immunologist at the Fred Hutchinson Cancer Research Center in Seattle (USA), where his main interest is dissecting the phenotype and function of human immune cells in non-lymphoid tissues during steady state and disease. He focuses specifically on myeloid cells, and in 2018 published one of the first 30-parameter OMIPs for the phenotyping of human dendritic cells (DCs).Over the past decade, Florian has been working extensively with different advanced cytometry platforms (conventional, spectral and mass cytometry) and recently developed an interest in single cell sequencing technologies. Since 2017 he is an ISAC Marylou scholar and has been actively engaged in teaching flow cytometry courses, in particular systematic panel design and analysis of high-dimensional cytometry experiments.
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Dr. Nicole Poulton is the Director of the Center for Aquatic Cytometry, and a Research Scientist at Bigelow Laboratory for Ocean Sciences. Nicole’s main research interests focus primarily on phytoplankton and aquatic microbial ecology, including harmful algal blooms and the role of phytoplankton in the global carbon cycle. Her research uses aquatic cytometry, single cell sorting and genomics to examine phytoplankton and bacterioplankton in the oceanic environment across the globe. She has over 25 years of flow cytometric experience within the aquatic sciences. Nicole received a BS and BA in Biology and Chemistry from Virginia Tech, and completed her PhD in Biological Oceanography from the Massachusetts Institute of Technology and Woods Hole Oceanographic Institution Joint Program. She joined Bigelow Laboratory in 2001 as a Postdoc and became a Research Scientist in 2008 and Director of the Center for Aquatic Cytometry in 2014. Nicole is very active in education and outreach and is also an ISAC Shared Resource Laboratory Emerging Leader (2017-2021).
Paola Bonfanti is group leader at the Francis Crick Institute in London and Principal Investigator at the UCL Great Ormond Street Institute of Child Health. Paola graduated in Medicine and Surgery from the University of Milan and subsequently moved to the Sanford-Burnham Institute in La Jolla, California. In 2008 she completed her PhD at the EPFL in Lausanne with a work demonstrating the plasticity and stemness of thymic epithelial cells under the supervision of Professor Yann Barrandon. In 2010, she obtained an EMBO Long Term Fellowship and moved to the Diabetes Research Centre in Brussels to work on pancreas regeneration. In 2011 Paola was awarded a Young Investigator Award in Innovative Therapy for Diabetes (EFSD/JDRF/Roche) and during her period in Brussels she contributed to several publications focusing on potency of expandable pancreatic progenitors. In 2013 Paola was awarded a UCL-Rosetrees Excellence Fellowship to pursue her interest in epithelial stem cell biology and regenerative medicine at UCL. In 2015 she obtained a Starting Grant from the European Research Council (ERC) for her project on thymus biology and in 2017 she joined the Francis Crick Institute as a group leader.
Theresia (Marisa) Westers
Theresia M. Westers, PhD, is a senior scientist at the department of Haematology/Cancer Center Amsterdam at the Amsterdam University Medical Center, Vrije Universiteit, Amsterdam, The Netherlands. She studied Clinical Chemistry and specialized in haematology and flow cytometry. The subject of her PhD training was ‘Dendritic cell-based immunotherapy in acute myeloid leukemia’. Besides daily supervision of flow cytometry diagnostics in haematological malignancies at the Amsterdam UMC, she is an active member of the International European LeukemiaNet Working group on Flow Cytometry in Myelodysplastic Syndromes (MDS) including co-authorship of MDS flow cytometry guideline papers. She is involved in education regarding basic flow cytometry in Haematology at the Vrije Universiteit and Amstel Academy, Amsterdam, in the Doctor2Doctor outreach program in Eldoret, Kenya, and in education of MDS flow cytometry at the ESCCA/Prague Flow Cytometry School. Focus of her research concerns MDS: flow cytometry-based diagnostic tools, risk stratification and treatment-monitoring, disease-initiating stem cells and immunopathogenesis.
Elaine Coustan-Smith FIBMS FRCPath is Principal Research Scientist in the Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore. Before moving to Singapore, she was Laboratory Manager in the Department of Oncology at St Jude Children’s Research Hospital in Memphis, Tennessee, and Chief Medical Laboratory Scientific Officer in the Department of Immunology at the Royal Free Hospital, London. Her main research interests are the development of novel approaches to the classification of leukemia and lymphoma, minimal residual disease testing, and monitoring immune cells during adoptive cell therapy of cancer. She has authored more than 100 publications.
Speaker profile details coming soon:
Australasian invited speakers include:
Dr Robert Weinkove is Clinical Director at the Malaghan Institute of Medical Research (MIMR), and holds a joint appointment as a Consultant Haematologist at Wellington Blood & Cancer Centre. After studying medicine at the University of Cambridge and Kings College London, he trained in haematology in London and Germany. He was awarded a PhD from the University of Otago in 2012.
Dr Weinkove leads the chimeric antigen receptor (CAR) T-cell programme at the Malaghan Institute. This includes provision of clinical oversight for the cellular therapy facility at the Malaghan Institute, which manufactures clinical-grade lentiviral vectors and CAR T-cells. He is Principal Investigator for ‘ENABLE’ (ClinicalTrials.gov reference NCT04049513), a phase I study of a new third-generation CAR T-cell product (WZTL-002) for relapsed and refractory lymphoma. Flow cytometric assays are integral to this trial, and are employed for manufacturing research and development, lentiviral vector titration, CAR T-cell product release testing and characterisation, trial screening procedures, and exploratory endpoint analysis.
Stay tuned as more speakers and profiles will be added soon!